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Varela-López et al., 2019 - Google Patents

An update on the mechanisms related to cell death and toxicity of doxorubicin and the protective role of nutrients

Varela-López et al., 2019

Document ID
11373093687733104259
Author
Varela-López A
Battino M
Navarro-Hortal M
Giampieri F
Forbes-Hernández T
Romero-Márquez J
Collado R
Quiles J
Publication year
Publication venue
Food and Chemical Toxicology

External Links

Snippet

Doxorubicin (DOX), is a very effective chemotherapeutic agent against cancer whose clinical use is limited by toxicity. Different strategies have been proposed to attenuate toxicity, including combined therapy with bioactive compounds. This review update mechanisms of …
Continue reading at www.sciencedirect.com (other versions)

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    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
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