Pistillo et al., 1986 - Google Patents
In vitro production of a human HLA alloantibody of restricted specificity (DQw2) via Epstein-Barr virus transformationPistillo et al., 1986
- Document ID
- 11110318715170747993
- Author
- Pistillo M
- Hämmerling U
- Dupont B
- Ferrara G
- Publication year
- Publication venue
- Human Immunology
External Links
Snippet
This paper describes the in vitro production of the human alloantibody 454A. C5 with HLA- DQw2 specificity produced by a stable EBV-transformed cell line. Immune B cells for transformation were generated by planned immunization of a blood donor volunteer with …
- 238000004519 manufacturing process 0 title abstract description 8
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material Not used, see subgroups
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses, e.g. hepatitis E virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US4720459A (en) | Myelomas for producing human/human hybridomas | |
Goding | Antibody production by hybridomas | |
US4594325A (en) | High fusion frequency fusible lymphoblastoid cell line | |
Lake et al. | Production and characterization of cytotoxic Thy‐1 antibody‐secreting hybrid cell lines Detection of T cell subsets | |
Sanders et al. | Characterization of the physical interaction between antigen-specific B and T cells. | |
Foung et al. | Rescue of human monoclonal antibody production from an EBV-transformed B cell line by fusion to a human-mouse hybridoma | |
Arnold et al. | Antigen-induced lymphomagenesis: identification of a murine B cell lymphoma with known antigen specificity. | |
Goossens et al. | Human monoclonal antibodies against blood group antigens: preparation of a series of stable EBV immortalized B clones producing high levels of antibody of different isotypes and specificities | |
Pistillo et al. | In vitro production of a human HLA alloantibody of restricted specificity (DQw2) via Epstein-Barr virus transformation | |
Lohmeyer et al. | A subset of human natural killer cells isolated and characterized by monoclonal antibodies | |
EP0124717A2 (en) | Human monoclonal antibodies to cancer cells | |
WO1982003089A1 (en) | Monoclonal antibody | |
US4517289A (en) | Monoclonal antibodies for human tissue cross-matching | |
Hämmerling et al. | Immunofluorescence analysis of Ig determinants of mouse thymocytes and T cells | |
US4818689A (en) | Late differentiation antigen associated with helper T lymphocyte function | |
Pickering et al. | A human myeloma cell line that does not express immunoglobulin but yields a high frequency of antibody-secreting hybridomas. | |
AU607134B2 (en) | Human anti-rhesus D producing heterohybridomas | |
JPS6054687A (en) | Production of monoclone antibody | |
Yoshie et al. | Anti-phosphorylcholine antibody-producing cells in human lymphoblastoid cell lines established by transformation with Epstein-Barr virus | |
EP0107528B1 (en) | Human nonsecretory plasmacytoid cell line | |
Glass et al. | Requirement for MHC class II positive accessory cells in an antigen specific bovine T cell response | |
Lafrenz et al. | Surface IgG-bearing cells retain the capacity to secrete IgM. | |
EP0204522A2 (en) | Monoclonal antibody panel for histocompatibility typing | |
Sidman et al. | Proliferative response to anti-IgM antibodies of various B lymphocyte subpopulations isolated by cell sorting | |
Stricker et al. | A Human Monoclonal IgG1λ Anti‐Hepatitis B Surface Antibody: Production, Properties, and Applications |