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Zhou et al., 2020 - Google Patents

64Cu-labeled melanin nanoparticles for PET/CT and radionuclide therapy of tumor

Zhou et al., 2020

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Document ID
11046459766546186730
Author
Zhou H
Zhang Q
Cheng Y
Xiang L
Shen G
Wu X
Cai H
Li D
Zhu H
Zhang R
Li L
Cheng Z
Publication year
Publication venue
Nanomedicine: Nanotechnology, Biology and Medicine

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Snippet

Melanin is a group of natural pigments found in living organism. It can be used for positron emission tomography (PET) imaging due to its inherent chelating ability to radioactive cupric ion. This study was to prepare 64 Cu-labeled PEGylated melanin nanoparticles (64 Cu-PEG …
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    • A61K51/04—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus organic compounds
    • A61K51/0474—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
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