Nasti et al., 2015 - Google Patents
MC 1R, Eumelanin and Pheomelanin: Their role in determining the susceptibility to skin cancerNasti et al., 2015
View PDF- Document ID
- 10960428909848833775
- Author
- Nasti T
- Timares L
- Publication year
- Publication venue
- Photochemistry and photobiology
External Links
Snippet
Skin pigmentation is due to the accumulation of two types of melanin granules in the keratinocytes. Besides being the most potent blocker of ultraviolet radiation, the role of melanin in photoprotection is complex. This is because one type of melanin called …
- 201000000849 skin cancer 0 title abstract description 17
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K8/00—Cosmetic or similar toilet preparations
- A61K8/18—Cosmetic or similar toilet preparations characterised by the composition
- A61K8/30—Cosmetic or similar toilet preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetic or similar toilet preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetic or similar toilet preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetic or similar toilet preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetic or similar toilet preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Nasti et al. | MC 1R, Eumelanin and Pheomelanin: Their role in determining the susceptibility to skin cancer | |
Slominski et al. | Melanin pigmentation in mammalian skin and its hormonal regulation | |
Slominski et al. | Melanoma, melanin, and melanogenesis: The Yin and Yang relationship | |
Sulaimon et al. | The biology of melanocytes | |
Lin et al. | Melanocyte biology and skin pigmentation | |
Hsiao et al. | The roles of microphthalmia-associated transcription factor and pigmentation in melanoma | |
Ito et al. | Quantitative analysis of eumelanin and pheomelanin in humans, mice, and other animals: a comparative review | |
Wakamatsu et al. | Diversity of pigmentation in cultured human melanocytes is due to differences in the type as well as quantity of melanin | |
Tobin | Human hair pigmentation–biological aspects | |
Miot et al. | Physiopathology of melasma | |
Choi et al. | IL-4 inhibits the melanogenesis of normal human melanocytes through the JAK2–STAT6 signaling pathway | |
Beaumont et al. | Melanocortin MC1 receptor in human genetics and model systems | |
Hida et al. | Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast‐like alteration of melanocytes: a cAMP‐independent pathway | |
Guida et al. | MC1R functions, expression, and implications for targeted therapy | |
Choi et al. | Kojic acid-induced IL-6 production in human keratinocytes plays a role in its anti-melanogenic activity in skin | |
Lee et al. | The regulation of epidermal melanogenesis via cAMP and/or PKC signaling pathways: insights for the development of hypopigmenting agents | |
Chang et al. | CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation | |
Hearing | The regulation of melanin formation | |
Premi | Role of melanin chemiexcitation in melanoma progression and drug resistance | |
Roulin et al. | Pale and dark reddish melanic tawny owls differentially regulate the level of blood circulating POMC prohormone in relation to environmental conditions | |
Suzuki et al. | Melanogenic effect of dersimelagon (MT‐7117), a novel oral melanocortin 1 receptor agonist | |
Yoo et al. | CRTC3, a sensor and key regulator for melanogenesis, as a tunable therapeutic target for pigmentary disorders | |
Miller et al. | New insights into pigmentary pathways and skin cancer | |
Lee et al. | N-(3, 5-dimethylphenyl)-3-methoxybenzamide (A3B5) targets TRP-2 and inhibits melanogenesis and melanoma growth | |
Sato et al. | Acerola (Malpighia emarginata DC.) juice intake suppresses UVB-induced skin pigmentation in SMP30/GNL knockout hairless mice |