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Seczynska et al., 2022 - Google Patents

Genome surveillance by HUSH-mediated silencing of intronless mobile elements

Seczynska et al., 2022

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Document ID
1095277056256574103
Author
Seczynska M
Bloor S
Cuesta S
Lehner P
Publication year
Publication venue
Nature

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Snippet

All life forms defend their genome against DNA invasion. Eukaryotic cells recognize incoming DNA and limit its transcription through repressive chromatin modifications. The human silencing hub (HUSH) complex transcriptionally represses long interspersed element …
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    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
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