[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Devine et al., 2011 - Google Patents

Parkinson's disease and α‐synuclein expression

Devine et al., 2011

View PDF
Document ID
10948917473562060610
Author
Devine M
Gwinn K
Singleton A
Hardy J
Publication year
Publication venue
Movement Disorders

External Links

Snippet

Genetic studies of Parkinson's disease over the last decade or more have revolutionized our understanding of this condition. α‐Synuclein was the first gene to be linked to Parkinson's disease, and is arguably the most important: the protein is the principal constituent of Lewy …
Continue reading at pmc.ncbi.nlm.nih.gov (PDF) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Hybridisation probes
    • C12Q1/6883—Hybridisation probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer

Similar Documents

Publication Publication Date Title
Devine et al. Parkinson's disease and α‐synuclein expression
Wood-Kaczmar et al. Understanding the molecular causes of Parkinson's disease
Li et al. PARK genes link mitochondrial dysfunction and alpha-synuclein pathology in sporadic Parkinson’s disease
Dawson et al. The role of parkin in familial and sporadic Parkinson's disease
Yokoseki et al. TDP‐43 mutation in familial amyotrophic lateral sclerosis
Stroo et al. Cellular regulation of amyloid formation in aging and disease
Venda et al. α-Synuclein and dopamine at the crossroads of Parkinson's disease
Hardy et al. Genes and parkinsonism
Sidhu et al. The role of α‐synuclein in both neuroprotection and neurodegeneration
Trossbach et al. Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits
Rohé et al. Homozygous PINK1 C‐terminus mutation causing early‐onset parkinsonism
Schapira Mitochondria in the aetiology and pathogenesis of Parkinson's disease
Libert et al. SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive
Tofaris Lysosome‐dependent pathways as a unifying theme in Parkinson's disease
Spillantini et al. Tau pathology and neurodegeneration
Lohmann et al. How much phenotypic variation can be attributed to parkin genotype?
Walker Huntington's disease
Reitz et al. SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk
Brenner et al. Update on genetics of amyotrophic lateral sclerosis
Beyer et al. Differential expression of α‐synuclein isoforms in dementia with Lewy bodies
Rüb et al. Spinocerebellar ataxia type 3 (SCA3): thalamic neurodegeneration occurs independently from thalamic ataxin‐3 immunopositive neuronal intranuclear inclusions
Sudhaman et al. Evidence of mutations in RIC3 acetylcholine receptor chaperone as a novel cause of autosomal-dominant Parkinson's disease with non-motor phenotypes
Aasly Long-term outcomes of genetic Parkinson’s disease
Hofmann et al. RNA binding proteins and the pathogenesis of frontotemporal lobar degeneration
Rajendram et al. Glutamate genetics in obsessive-compulsive disorder: a review