Yan, 2010 - Google Patents
Artemis Interacts With The Cul4A Ubiquitin E3 Ligase Complex And Regulates The Cell Cycle ProgressionYan, 2010
View PDF- Document ID
- 10746119132380883720
- Author
- Yan Y
- Publication year
External Links
Snippet
There are several individuals whom I would like to take this opportunity to thank. I would like to thank my family for their support along my way to becoming a scientist. I owe thanks to the faculties who had served and are serving on my committee, Dr. Lei Li, Dr. Mong-Hong Lee …
- 230000022131 cell cycle 0 title abstract description 62
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/564—Immunoassay; Biospecific binding assay for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Vandamme et al. | Interaction proteomics analysis of polycomb proteins defines distinct PRC1 complexes in mammalian cells | |
Mukherjee et al. | Lipid-dependent recruitment of neuronal Src to lipid rafts in the brain | |
Sossey-Alaoui et al. | c-Abl-mediated phosphorylation of WAVE3 is required for lamellipodia formation and cell migration | |
Lin et al. | PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum | |
Sivasubramaniam et al. | Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1 | |
Masuda et al. | TRIM29 regulates the assembly of DNA repair proteins into damaged chromatin | |
Perez‐Oliva et al. | USP 45 deubiquitylase controls ERCC 1–XPF endonuclease‐mediated DNA damage responses | |
Mund et al. | Disinhibition of the HECT E3 ubiquitin ligase WWP2 by polymerized Dishevelled | |
Yan et al. | Artemis interacts with the Cul4A-DDB1DDB2 ubiquitin E3 ligase and regulates degradation of the CDK inhibitor p27 | |
Li et al. | CRL ubiquitin ligases and DNA damage response | |
Lukong et al. | BRK phosphorylates PSF promoting its cytoplasmic localization and cell cycle arrest | |
Fan et al. | FAM122A, a new endogenous inhibitor of protein phosphatase 2A | |
Girouard et al. | RhoA proteolysis regulates the actin cytoskeleton in response to oxidative stress | |
Kanamarlapudi | Exchange factor EFA6R requires C-terminal targeting to the plasma membrane to promote cytoskeletal rearrangement through the activation of ADP-ribosylation factor 6 (ARF6) | |
Strauss et al. | MDC1 is ubiquitylated on its tandem BRCT domain and directly binds RAP80 in a UBC13-dependent manner | |
Yan | Artemis Interacts With The Cul4A Ubiquitin E3 Ligase Complex And Regulates The Cell Cycle Progression | |
Chiticariu et al. | CENPV Is a CYLD-Interacting Molecule Regulating Ciliary Acetylated α-Tubulin | |
US20070072210A1 (en) | Use of brca1-associated protein to treat and screen for dna damage and to identify therapeutics that promote a dna damage response | |
Dinarina et al. | Negative regulation of cell-cycle progression by RINGO/Speedy E | |
Roy et al. | A phospho-regulated signal motif determines subcellular localization of α-TAT1 for dynamic microtubule acetylation | |
川原弘明 | Functional analysis of DCAF7 and ERCC1-XPF interaction identified by affinity-purification and mass spectrometry | |
Tran | Regulation of Composition and Functions of SWI/SNF Chromatin Remodeling Complex | |
Abdelbaki | Investigating how ubiquitin-mediated proteolysis of AURKA contributes to its activity in the cell cycle | |
Gama Braga | The function of the pseudokinase domain of BUBR1 in mitosis | |
Anderson | Elucidating the ZYG11 Protein Interactions Controlling Mitotic Slippage and a Novel Quiescence Pathway |