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Van Der Vliet et al., 2001 - Google Patents

Potent expansion of human natural killer T cells using α-galactosylceramide (KRN7000)-loaded monocyte-derived dendritic cells, cultured in the presence of IL-7 and …

Van Der Vliet et al., 2001

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Document ID
10567446081043566581
Author
Van Der Vliet H
Nishi N
Koezuka Y
Von Blomberg B
Van Den Eertwegh A
Porcelli S
Pinedo H
Scheper R
Giaccone G
Publication year
Publication venue
Journal of immunological methods

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Snippet

Natural killer T (NKT) cells have an extremely restricted T-cell receptor repertoire, in man consisting of a Vα24 chain preferentially paired with a Vβ11 chain, and play crucial roles in various immune responses. Characterization of circulating Vα24+ Vβ11+-T cells is …
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
    • A—HUMAN NECESSITIES
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