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Dewey et al., 1951 - Google Patents

Growth inhibition in Tetrahymena by folic acid analogs.

Dewey et al., 1951

Document ID
10210436509130799187
Author
Dewey V
Kidder G
Parks Jr R
Publication year
Publication venue
Proceedings of the Society for Experimental Biology and Medicine

External Links

Snippet

Summary The antifolics, 4-amino-9-methylpteroylglutamic acid (A-ninopterin), 4-amino-10- methylpteroylglutamic acid (A-methopterin) and 4-amino-9; 10-dimethyl-pteroylglutamic acid (A-denopterin) are all inhibitory to Tetrahymena. The inhibition produced by A-ninopterin is …
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid

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