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Ak et al., 2021 - Google Patents

Brain-targeted, drug-loaded solid lipid nanoparticles against glioblastoma cells in culture

Ak et al., 2021

Document ID
10062158423504907467
Author
Ak G
Ünal A
Karakayalı T
Özel B
Günel N
Şanlıer
Publication year
Publication venue
Colloids and Surfaces B: Biointerfaces

External Links

Snippet

The aim of this study was the preparation of solid lipid nanoparticles (SLN) formed from cetyl palmitate with having targeting molecules for monocarboxylate transporter-1 (MCT-1): β- hydroxybutyric acid and anticancer agents: carmustine (BCNU) and temozolomide (TMZ) for …
Continue reading at www.sciencedirect.com (other versions)

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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
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    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
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