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Mortezazadeh et al., 2019 - Google Patents

Gadolinium (III) oxide nanoparticles coated with folic acid-functionalized poly (β-cyclodextrin-co-pentetic acid) as a biocompatible targeted nano-contrast agent for …

Mortezazadeh et al., 2019

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Document ID
9907111826183625760
Author
Mortezazadeh T
Gholibegloo E
Alam N
Dehghani S
Haghgoo S
Ghanaati H
Khoobi M
Publication year
Publication venue
Magnetic Resonance Materials in Physics, Biology and Medicine

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Objectives In this study, a novel targeted MRI contrast agent was developed by coating gadolinium oxide nanoparticles (Gd 2 O 3 NPs) with β-cyclodextrin (CD)-based polyester and targeted by folic acid (FA). Materials and methods The developed Gd 2 O 3@ PCD–FA …
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    • A61K49/1827—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles coated or functionalised microparticles or nanoparticles coated or functionalised nanoparticles having a (super)(para)magnetic core, being a solid MRI-active material, e.g. magnetite, or composed of a plurality of MRI-active, organic agents, e.g. Gd-chelates, or nuclei, e.g. Eu3+, encapsulated or entrapped in the core of the coated or functionalised nanoparticle
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