[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Wu et al., 2020 - Google Patents

Absolute quantitative imaging of sphingolipids in brain tissue by exhaustive liquid microjunction surface sampling–liquid chromatography–mass spectrometry

Wu et al., 2020

Document ID
973501934376748934
Author
Wu Q
Huang Z
Wang Y
Zhang Z
Lu H
Publication year
Publication venue
Journal of Chromatography A

External Links

Snippet

It is challenging to achieve absolute quantitation and accurate identification with mass spectrometry imaging (MSI) techniques. The issues facing these techniques include the uncertainty of sampling and ionization efficiencies in a localized environment, the difficulty in …
Continue reading at www.sciencedirect.com (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or superfluid chromatograph
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8665—Signal analysis for calibrating the measuring apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
    • G01N30/94—Development
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2560/00—Chemical aspects of mass spectrometric analysis of biological material

Similar Documents

Publication Publication Date Title
Wu et al. Absolute quantitative imaging of sphingolipids in brain tissue by exhaustive liquid microjunction surface sampling–liquid chromatography–mass spectrometry
US11698361B1 (en) Method of processing a biological sample
Chetwynd et al. A review of nanoscale LC-ESI for metabolomics and its potential to enhance the metabolome coverage
Wang et al. Applications of mass spectrometry for cellular lipid analysis
Škrášková et al. Enhanced capabilities for imaging gangliosides in murine brain with matrix-assisted laser desorption/ionization and desorption electrospray ionization mass spectrometry coupled to ion mobility separation
Wolrab et al. Oncolipidomics: Mass spectrometric quantitation of lipids in cancer research
Wang et al. Hydroxyflavones as a new family of matrices for MALDI tissue imaging
US11061005B2 (en) Mass spectrometry assay method for detection and quantitation of organic acid metabolites
Paglia et al. Desorption electrospray ionization mass spectrometry analysis of lipids after two-dimensional high-performance thin-layer chromatography partial separation
US20220050090A1 (en) Mass spectrometry assay method for detection and quantitation of microbiota related metabolites
US9685311B2 (en) Methods for detecting reverse triiodothyronine by mass spectrometry
Sanchez et al. Mass spectrometry imaging of diclofenac and its metabolites in tissues using nanospray desorption electrospray ionization
Duncan et al. Spatially defined surface sampling capillary electrophoresis mass spectrometry
Wu et al. Quantitative mass spectrometry imaging of amino acids with isomer differentiation in brain tissue via exhaustive liquid microjunction surface sampling–tandem mass tags labeling–ultra performance liquid chromatography–mass spectrometry
Saunders et al. Spatial single cell metabolomics: current challenges and future developments
He et al. Analytical techniques for biomass-restricted metabolomics: An overview of the state-of-the-art
JP2020530904A (en) Detection and quantification of guanidinoacetic acid, creatine, and creatinine by mass spectrometry
US9880147B2 (en) Free and total fatty acid determination using desorption ionization—mass spectrometry
Zhao et al. Mass spectrometry imaging: applications in drug distribution studies
Lukowski et al. An optimized approach and inflation media for obtaining complimentary mass spectrometry-based omics data from human lung tissue
US11333628B2 (en) Chemical class compositions from collision cross-section fragment ions
Wu et al. Quantitative mass spectrometry imaging with liquid microjunction surface sampling
Woods et al. The application and potential of ion mobility mass spectrometry in imaging MS with a focus on lipids
Wang et al. Nanoparticle-based applications by atmospheric pressure matrix assisted desorption/ionization mass spectrometry
Zhao et al. Serum lipidomics study of Ding-Zhi-Xiao-Wan effect on Alzheimer's disease using online liquid extraction surface analysis coupled to direct infusion mass spectrometry