[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Simpson et al., 1984 - Google Patents

Insulin receptor phosphorylation may not be a prerequisite for acute insulin action

Simpson et al., 1984

Document ID
9682350798869397533
Author
Simpson I
Hedo J
Publication year
Publication venue
Science

External Links

Snippet

An antiserum to the insulin receptor mimicked insulin's acute actions on glucose transport, phosphorylation of integral membrane proteins, and internalization of the insulin receptor in isolated rat adipose cells. These insulinomimetic actions of the antiserum occurred without …
Continue reading at www.science.org (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
    • A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor

Similar Documents

Publication Publication Date Title
Simpson et al. Insulin receptor phosphorylation may not be a prerequisite for acute insulin action
US5433946A (en) Synthesis and utilization of therapeutic agents for the treatment of lysosomal storage diseases
Häring et al. Insulin receptor phosphorylation in intact adipocytes and in a cell-free system
US4847240A (en) Method of effecting cellular uptake of molecules
De Wied Inhibitory effect of ACTH and related peptides on extinction of conditioned avoidance behavior in rats
US4701521A (en) Method of effecting cellular uptake of molecules
Stone et al. Effect of estradiol-17β on preprolactin messenger ribonucleic acid activity in the rat pituitary gland
Koliatsos et al. Recombinant human nerve growth factor prevents retrograde degeneration of axotomized basal forebrain cholinergic neurons in the rat
US4749570A (en) Targeting conjugates of albumin and therapeutic agents
Kano et al. Polyamine transport and metabolism in mouse mammary gland. General properties and hormonal regulation.
Van Obberghen et al. Insulin-receptor antibodies mimic a late insulin effect
Hwang et al. Characterization of low density and high density lipoprotein receptors in the rat corpus luteum and regulation by gonadotropin.
Burant et al. In vitro and in vivo activation of the insulin receptor kinase in control and denervated skeletal muscle.
Zick et al. Insulin stimulates phosphorylation of serine residues in soluble insulin receptors
WO1988000834A1 (en) Chimeric peptides for neuropeptide delivery through the blood-brain barrier
DE1213032T1 (en) Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and equipment therefor
Poznansky et al. Growth hormone‐albumin conjugates Reduced renal toxicity and altered plasma clearance
WO1979000515A1 (en) Method of effecting cellular uptake of molecules
EP0119650A2 (en) Galactosyl-insulin conjugates useful in treating diabetics
Caraglia et al. Interferon α 2 recombinant and epidermal growth factor modulate proliferation and hypusine synthesis in human epidermoid cancer KB cells
McKenzie et al. Pancreatic spasmolytic polypeptide protects the gastric mucosa but does not inhibit acid secretion or motility
CN104906576B (en) For hypodermic high concentration anti-VEGF antibody preparaton
Riordan et al. Human angiogenin, an organogenic protein
Jeejeebhoy et al. Effects of hormones on the synthesis of α1 (acute-phase) glycoprotein in isolated rat hepatocytes
DAVIDSON et al. Insulin and Sepharose-insulin effects on tyrosine transaminase levels in cultured rat liver cells