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Zhou et al., 2011 - Google Patents

Endosomal pH-activatable poly (ethylene oxide)-graft-doxorubicin prodrugs: synthesis, drug release, and biodistribution in tumor-bearing mice

Zhou et al., 2011

Document ID
9587838406764424390
Author
Zhou L
Cheng R
Tao H
Ma S
Guo W
Meng F
Liu H
Liu Z
Zhong Z
Publication year
Publication venue
Biomacromolecules

External Links

Snippet

Novel poly (ethylene oxide)-graft-doxorubicin (PEO-g-DOX) prodrugs with DOX covalently conjugated to PEO via a pH-sensitive hydrazone bond were developed. PEO-g-DOX conjugates could be readily prepared in the following steps:(i) anionic ring-opening …
Continue reading at pubs.acs.org (other versions)

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