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Xu et al., 2018 - Google Patents

Reversing abnormal neural development by inhibiting OLIG2 in down syndrome human iPSC brain organoids and neuronal mouse chimeras

Xu et al., 2018

View PDF
Document ID
9513400383578622439
Author
Xu R
Brawner A
Li S
Kim H
Xue H
Pang Z
Kim W
Hart R
Liu Y
Jiang P
Publication year
Publication venue
BioRxiv

External Links

Snippet

Down syndrome (DS), caused by triplication of human chromosome 21 (HSA21), is the most common genetic origin of intellectual disability. Despite the limited success of current pharmacological interventions, little has been achieved to reverse the abnormal brain …
Continue reading at www.biorxiv.org (PDF) (other versions)

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