[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Xu et al., 2019 - Google Patents

Systematic optimization and evaluation of sample pretreatment methods for LC-MS-based metabolomics analysis of adherent mammalian cancer cells

Xu et al., 2019

Document ID
9408231144930417171
Author
Xu X
Zang Q
Zhang R
Liu J
He J
Zhang R
Abliz Z
Publication year
Publication venue
Analytical Methods

External Links

Snippet

Cell metabolomics is a valuable tool in oncology. To obtain a valid description of the intracellular metabolome, sample pretreatment is critical to the metabolomics workflow, as this step might influence the reliability of research outcomes. Here we report a systematic …
Continue reading at pubs.rsc.org (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes

Similar Documents

Publication Publication Date Title
Ma et al. Advances in mass spectrometry imaging for spatial cancer metabolomics
Danzi et al. To metabolomics and beyond: a technological portfolio to investigate cancer metabolism
Patti et al. Metabolomics: the apogee of the omics trilogy
Ser et al. Extraction parameters for metabolomics from cultured cells
Kohler et al. Analytical pitfalls and challenges in clinical metabolomics
Liu et al. Single cell metabolomics using mass spectrometry: Techniques and data analysis
Vuckovic Current trends and challenges in sample preparation for global metabolomics using liquid chromatography–mass spectrometry
Zhang et al. Modern analytical techniques in metabolomics analysis
Chen et al. Combining desorption electrospray ionization mass spectrometry and nuclear magnetic resonance for differential metabolomics without sample preparation
Watrous et al. The evolving field of imaging mass spectrometry and its impact on future biological research
Ting et al. Normalization and statistical analysis of quantitative proteomics data generated by metabolic labeling
Schripsema Application of NMR in plant metabolomics: techniques, problems and prospects
Stopka et al. Ambient metabolic profiling and imaging of biological samples with ultrahigh molecular resolution using laser ablation electrospray ionization 21 Tesla FTICR mass spectrometry
Soste et al. A sentinel protein assay for simultaneously quantifying cellular processes
Maniscalco et al. Clinical metabolomics of exhaled breath condensate in chronic respiratory diseases
US6258605B1 (en) Clinical method for the genetic screening of newborns using tandem mass spectrometry
CN104297355A (en) Simulative-target metabonomics analytic method based on combination of liquid chromatography and mass spectrum
Wang et al. MS imaging of multicellular tumor spheroids and organoids as an emerging tool for personalized medicine and drug discovery
CN103592389A (en) LC/MS (liquid chromatography-mass spectrometer) metabonomics analysis method based on serum of GDM (gestational diabetes mellitus) patient
WO2020199866A1 (en) Biometabolomics data processing and analysis methods and apparatuses, and application thereof
Zhou et al. Systematic evaluation of serum and plasma collection on the endogenous metabolome
Chekmeneva et al. Ultra-Performance liquid chromatography–high-resolution mass spectrometry and direct infusion–high-resolution mass spectrometry for combined exploratory and targeted metabolic profiling of human urine
Xu et al. Systematic optimization and evaluation of sample pretreatment methods for LC-MS-based metabolomics analysis of adherent mammalian cancer cells
Jiang et al. Direct identification of forensic body fluids by MALDI-MS
Thompson et al. An enhanced isotopic fine structure method for exact mass analysis in discovery metabolomics: FIA-CASI-FTMS