Xing et al., 2023 - Google Patents
Progress toward the development of an effective vaccine for Extraintestinal pathogenic E. coli (ExPEC): The application of the multiple-protein subunits vaccine in …Xing et al., 2023
View PDF- Document ID
- 9118668899262359011
- Author
- Xing Y
- Clark J
- Chang J
- Zulk J
- Chirman D
- Piedra F
- Patras K
- Maresso A
- Publication year
- Publication venue
- bioRxiv
External Links
Snippet
Extraintestinal pathogenic E. coli (ExPEC) is the primary Gram-negative bacterial pathogen, and the leading cause of life-threatening sepsis and urinary tract infections (UTI) in adults. The emergence and increasing prevalence of multidrug-resistance (MDR) ExPEC strains …
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0291—Yersinia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Dziva et al. | Colibacillosis in poultry: unravelling the molecular basis of virulence of avian pathogenic Escherichia coli in their natural hosts | |
| Li et al. | Identification of a novel vaccine candidate by immunogenic screening of Vibrio parahaemolyticus outer membrane proteins | |
| JP2020019801A (en) | Attenuated live vaccines | |
| Dennehy et al. | Immunoproteomics: the key to discovery of new vaccine antigens against bacterial respiratory infections | |
| O'Bier et al. | Human and veterinary vaccines for Lyme disease | |
| Andersson et al. | Identification of new virulence factors and vaccine candidates for Yersinia pestis | |
| KR102071743B1 (en) | A novel live attenuated shigella vaccine | |
| Rodrigues et al. | Development and evaluation of a new recombinant protein vaccine (YidR) against Klebsiella pneumoniae infection | |
| Sun et al. | Pseudomonas fluorescens: iron-responsive proteins and their involvement in host infection | |
| US9597386B2 (en) | Outer membrane proteins of Histophilus somni and methods thereof | |
| Jing et al. | Oligomerization of IC43 resulted in improved immunogenicity and protective efficacy against Pseudomonas aeruginosa lung infection | |
| US20130243779A1 (en) | Peptides protective against e. faecalis, methods and uses relating thereto | |
| Xing et al. | Progress toward the development of an effective vaccine for Extraintestinal pathogenic E. coli (ExPEC): The application of the multiple-protein subunits vaccine in different murine models | |
| US20220288183A1 (en) | Vaccine constructs and uses thereof against staphylococcus infections | |
| JP6401148B2 (en) | Antigens and antigen combinations | |
| Xing et al. | Progress toward a vaccine for extraintestinal pathogenic E. coli (ExPEC) II: efficacy of a toxin-autotransporter dual antigen approach | |
| WO2024173855A2 (en) | Hemolysin antigens and vaccine embodiments for bacterial infection | |
| CN102209724A (en) | Non-typhoidal salmonella vaccines | |
| AU2004296394A1 (en) | Orally-administered live bacterial vaccines for plague | |
| Wang et al. | TLR4 agonist combined with trivalent protein JointS of Streptococcus suis provides immunological protection in animals. Vaccines (Basel). 2021; 9 (2): 184 | |
| Vij et al. | Dual immunization with CdtB protein and flagellin epitope offers augmented protection against enteric fever in mice | |
| JP2024540918A (en) | Lipopolysaccharide (LPS)-deficient Acinetobacter baumannii polyvalent vaccine | |
| Chen et al. | Vaccination with a trivalent Klebsiella pneumoniae vaccine confers protection in a murine model of pneumonia | |
| US20160030544A1 (en) | Immunogenic composition to neisseria | |
| Lim | The characterization of the lipoprotein VacJ in Burkholderia pseudomallei and Burkholderia thailandensis |