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Drais et al., 2022 - Google Patents

Investigation of lipid polymer hybrid nanocarriers for oral felodipine delivery: Formulation, method, in-vitro and ex-vivo evaluation

Drais et al., 2022

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Document ID
9103238934432707711
Author
Drais H
Hussein A
Publication year
Publication venue
Iraqi Journal of Pharmaceutical Sciences

External Links

Snippet

The antihypertensive felodipine is a calcium-channel blocking agent. It is practically insoluble in water and shows low oral bioavailability (15%-20%). This investigation aims to formulate and characterize felodipine lipid polymer hybrid nanocarriers (LPHNs) to be given …
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Classifications

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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
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    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
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