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Dong et al., 2011 - Google Patents

Role of microRNAs in cardiac hypertrophy, myocardial fibrosis and heart failure

Dong et al., 2011

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Document ID
8888247310635049428
Author
Dong D
Yang B
Publication year
Publication venue
Acta Pharmaceutica Sinica B

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Snippet

MicroRNAs (miRNAs) are endogenous small non-coding RNA molecules that post- transcriptionally regulate gene expression. MiRNA expression and function in heart disease remain to be determined but modulation of miRNA expression in vivo has revealed that …
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/14Type of nucleic acid interfering N.A.
    • C12N2310/141MicroRNAs, miRNAs
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    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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