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Zhang et al., 2013 - Google Patents

Novel quinic acid derivative KZ-41 prevents retinal endothelial cell apoptosis without inhibiting retinoblastoma cell death through p38 signaling

Zhang et al., 2013

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Document ID
8831431606042221851
Author
Zhang Q
Jiang Y
Toutounchian J
Wilson M
Morales-Tirado V
Miller D
Yates C
Steinle J
Publication year
Publication venue
Investigative Ophthalmology & Visual Science

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Purpose.: To determine whether a novel NF-κB inhibitor, KZ-41, can inhibit melphalan's actions on retinal endothelial cell (REC) inflammation and apoptosis, without eliminating the chemotherapeutic efficacy of melphalan on cell death of retinoblastoma cells (Y79) …
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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