Toka et al., 2004 - Google Patents
CD4+ CD25+ T cells regulate vaccine-generated primary and memory CD8+ T-cell responses against herpes simplex virus type 1Toka et al., 2004
View PDF- Document ID
- 8522601417970776819
- Author
- Toka F
- Suvas S
- Rouse B
- Publication year
- Publication venue
- Journal of virology
External Links
Snippet
It has become evident that naturally occurring CD25+ regulatory T cells (Treg cells) not only influence self-antigen specific immune response but also dampen foreign antigen specific immunity. This report extends our previous findings by demonstrating that immunity to …
- 210000001744 T-Lymphocytes 0 title abstract description 88
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Toka et al. | CD4+ CD25+ T cells regulate vaccine-generated primary and memory CD8+ T-cell responses against herpes simplex virus type 1 | |
| Stevenson et al. | Kinetic analysis of the specific host response to a murine gammaherpesvirus | |
| Marshall et al. | Virus-induced transient immune suppression and the inhibition of T cell proliferation by type I interferon | |
| Holtappels et al. | Enrichment of immediate-early 1 (m123/pp89) peptide-specific CD8 T cells in a pulmonary CD62Llo memory-effector cell pool during latent murine cytomegalovirus infection of the lungs | |
| Riberdy et al. | Diminished primary and secondary influenza virus-specific CD8+ T-cell responses in CD4-depleted Ig−/− mice | |
| Bollard et al. | T-cell therapy in the treatment of post-transplant lymphoproliferative disease | |
| Matloubian et al. | A role for perforin in downregulating T-cell responses during chronic viral infection | |
| Huber et al. | Cytokine production by Vγ+-T-cell subsets is an important factor determining CD4+-Th-cell phenotype and susceptibility of BALB/c mice to coxsackievirus B3-induced myocarditis | |
| Bourgeois et al. | CD8 lethargy in the absence of CD4 help | |
| Nandakumar et al. | Natural killer cells as novel helpers in anti-herpes simplex virus immune response | |
| Nelson et al. | Human cytomegalovirus glycoprotein B nucleoside-modified mRNA vaccine elicits antibody responses with greater durability and breadth than MF59-adjuvanted gB protein immunization | |
| Liu et al. | T-cell vaccination alters the course of murine herpesvirus 68 infection and the establishment of viral latency in mice | |
| Hengel et al. | Macrophages escape inhibition of major histocompatibility complex class I-dependent antigen presentation by cytomegalovirus | |
| Zhao et al. | Induction of anti-human immunodeficiency virus type 1 (HIV-1) CD8+ and CD4+ T-cell reactivity by dendritic cells loaded with HIV-1 X4-infected apoptotic cells | |
| Li et al. | Immunotherapy of murine retrovirus-induced acquired immunodeficiency by CD4 T regulatory cell depletion and PD-1 blockade | |
| Riddell et al. | Cytotoxic T cells specific for cytomegalovirus: a potential therapy for immunocompromised patients | |
| Yu et al. | Efficient induction of primary and secondary T cell-dependent immune responses in vivo in the absence of functional IL-2 and IL-15 receptors | |
| Aung et al. | Alternative mechanisms of respiratory syncytial virus clearance in perforin knockout mice lead to enhanced disease | |
| Rajasagi et al. | CD4+ T cells are required for the priming of CD8+ T cells following infection with herpes simplex virus type 1 | |
| Zhou et al. | Role of interferon regulatory factor 7 in T cell responses during acute lymphocytic choriomeningitis virus infection | |
| Sparks-Thissen et al. | An optimized CD4 T-cell response can control productive and latent gammaherpesvirus infection | |
| Kumaraguru et al. | Immunization with chaperone-peptide complex induces low-avidity cytotoxic T lymphocytes providing transient protection against herpes simplex virus infection | |
| Suresh et al. | Role of lymphotoxin α in T-cell responses during an acute viral infection | |
| Planz et al. | Borna disease virus nucleoprotein (p40) is a major target for CD8+-T-cell-mediated immune response | |
| Zhong et al. | Antibody-independent antiviral function of memory CD4+ T cells in vivo requires regulatory signals from CD8+ effector T cells |