[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Eibl et al., 2017 - Google Patents

Single pulse two photon fluorescence lifetime imaging (SP-FLIM) with MHz pixel rate

Eibl et al., 2017

View HTML @Full View
Document ID
8453289182520744651
Author
Eibl M
Karpf S
Weng D
Hakert H
Pfeiffer T
Kolb J
Huber R
Publication year
Publication venue
Biomedical optics express

External Links

Snippet

Two-photon-excited fluorescence lifetime imaging microscopy (FLIM) is a chemically specific 3-D sensing modality providing valuable information about the microstructure, composition and function of a sample. However, a more widespread application of this technique is …
Continue reading at opg.optica.org (HTML) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/636—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited using an arrangement of pump beam and probe beam; using the measurement of optical non-linear properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colour
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry; Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/84—Systems specially adapted for particular applications
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRA-RED, VISIBLE OR ULTRA-VIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colour
    • G01J3/12—Generating the spectrum; Monochromators
    • G01J3/1256—Generating the spectrum; Monochromators using acousto-optic tunable filter

Similar Documents

Publication Publication Date Title
Eibl et al. Single pulse two photon fluorescence lifetime imaging (SP-FLIM) with MHz pixel rate
Dowling et al. Fluorescence lifetime imaging with picosecond resolution for biomedical applications
Liao et al. Stimulated Raman spectroscopic imaging by microsecond delay-line tuning
Ozeki et al. High-speed molecular spectral imaging of tissue with stimulated Raman scattering
Bower et al. High-speed imaging of transient metabolic dynamics using two-photon fluorescence lifetime imaging microscopy
Chen et al. A multimodal platform for nonlinear optical microscopy and microspectroscopy
Xu et al. Spectroscopic spectral-domain optical coherence microscopy
Pohling et al. Chemoselective imaging of mouse brain tissue via multiplex CARS microscopy
Owen et al. Excitation-resolved hyperspectral fluorescence lifetime imaging using a UV-extended supercontinuum source
Ren et al. Terahertz coherent anti-Stokes Raman scattering microscopy
Nie et al. Multimodal microscopy with sub-30 fs Yb fiber laser oscillator
Yin et al. Video-rate mid-infrared photothermal imaging by single-pulse photothermal detection per pixel
Giacomelli et al. Rapid imaging of surgical breast excisions using direct temporal sampling two photon fluorescent lifetime imaging
Yu et al. Intravital confocal fluorescence lifetime imaging microscopy in the second near-infrared window
Sorrells et al. Single-photon peak event detection (SPEED): a computational method for fast photon counting in fluorescence lifetime imaging microscopy
Zhang et al. Investigation of signal-to-noise ratio in frequency-domain multiphoton fluorescence lifetime imaging microscopy
Qu et al. Temporally and spectrally resolved sampling imaging with a specially designed streak camera
Hinsdale et al. Optically sectioned wide-field fluorescence lifetime imaging microscopy enabled by structured illumination
Martins et al. Shifted-excitation Raman difference spectroscopy for in vitro and in vivo biological samples analysis
Zhao et al. Parallel excitation-emission multiplexed fluorescence lifetime confocal microscopy for live cell imaging
Dow et al. Video-rate two-photon excited fluorescence lifetime imaging system with interleaved digitization
Schie et al. Simultaneous forward and epi-CARS microscopy with a single detector by time-correlated single photon counting
Leveque-Fort et al. Fluorescence-lifetime imaging with a multifocal two-photon microscope
Shelton et al. Molecular specificity in photoacoustic microscopy by time-resolved transient absorption
Van Dijk et al. Rapid spectral-domain localization