[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Huang et al., 2015 - Google Patents

Recyclable organocatalyst‐promoted one‐pot asymmetric synthesis of spirooxindoles bearing multiple stereogenic centers

Huang et al., 2015

Document ID
8170243465232366086
Author
Huang X
Pham K
Yi W
Zhang X
Clamens C
Hyatt J
Jasinsk J
Tayvah U
Zhang W
Publication year
Publication venue
Advanced Synthesis & Catalysis

External Links

Snippet

A recyclable fluorous bifunctional Cinchona alkaloid/thiourea‐catalyzed and four‐ component Michael/Mannich/cyclization sequence has been developed for the asymmetric synthesis of spirooxindoles containing 2‐piperidinone and tetrahydropyridine rings. This …
Continue reading at onlinelibrary.wiley.com (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings

Similar Documents

Publication Publication Date Title
Huang et al. Recyclable organocatalyst‐promoted one‐pot asymmetric synthesis of spirooxindoles bearing multiple stereogenic centers
Chen et al. Tandem cross‐coupling/spirocyclization/Mannich‐type reactions of 3‐(2‐isocyanoethyl) indoles with diazo compounds toward polycyclic spiroindolines
He et al. A Gold‐Catalyzed Domino Cyclization Enabling Rapid Construction of Diverse Polyheterocyclic Frameworks
Liao et al. Highly enantioselective [3+ 2] coupling of indoles with quinone monoimines promoted by a chiral phosphoric acid
Liao et al. Asymmetric Brønsted acid catalyzed synthesis of triarylmethanes—construction of communesin and spiroindoline scaffolds
Lian et al. Rhodium (III)‐Catalyzed Alkenyl C H Bond Functionalization: Convergent Synthesis of Furans and Pyrroles
Wang et al. Synthesis of Quinolines by Visible‐Light Induced Radical Reaction of Vinyl Azides and α‐Carbonyl Benzyl Bromides
Tan et al. Tandem double‐Michael‐addition/cyclization/acyl migration of 1, 4‐dien‐3‐ones and ethyl isocyanoacetate: stereoselective synthesis of pyrrolizidines
Feng et al. Ligand controlled regiodivergent C1 insertion on arynes for construction of phenanthridinone and acridone alkaloids
Zhao et al. Cinchona Alkaloid‐Derived Thiourea‐Catalyzed Diastereo‐and Enantioselective [3+ 2] Cycloaddition Reaction of Isocyanoacetates to Isatins: A Facile Access to Optically Active Spirooxindole Oxazolines
Zhang et al. Enantioselective Synthesis of Unsymmetrical Diaryl‐Substituted Spirocyclohexanonepyrazolones through a Cascade [4+ 2] Double Michael Addition
Shi et al. Catalytic Asymmetric 1, 3‐Dipolar Cycloadditions of Alkynes with Isatin‐Derived Azomethine Ylides: Enantioselective Synthesis of Spiro [indoline‐3, 2′‐pyrrole] Derivatives
Rueping et al. General and Efficient Organocatalytic Synthesis of Indoloquinolizidines, Pyridoquinazolines and Quinazolinones through a One‐Pot Domino Michael Addition‐Cyclization‐Pictet–Spengler or 1, 2‐Amine Addition Reaction
Wang et al. Enantioselective desymmetrization of cyclobutanones enabled by synergistic palladium/enamine catalysis
Zhao et al. Organocatalytic [3+ 2] Cycloadditions of Barbiturate‐Based Olefins with 3‐Isothiocyanato Oxindoles: Highly Diastereoselective and Enantioselective Synthesis of Dispirobarbiturates
Wang et al. Catalytic Asymmetric Construction of 3, 3′‐Spirooxindoles Fused with Seven‐Membered Rings by Enantioselective Tandem Reactions
Jarrige et al. Enantioselective Organocatalytic Intramolecular Aza‐Diels–Alder Reaction
Li et al. Enantioselective Vinylogous Michael/Cyclization Cascade Reaction of Acyclic β, γ‐Unsaturated Amides with Isatylidene Malononitriles: Asymmetric Construction of Spirocyclic Oxindoles
Takizawa et al. Enantioselective organocatalyzed formal [4+ 2] cycloaddition of ketimines with allenoates: easy access to a tetrahydropyridine framework with a chiral tetrasubstituted stereogenic carbon center
An et al. The Construction of 3‐Methyl‐4‐arylpiperidines via a trans‐Perhydroindolic Acid‐Catalyzed Asymmetric Aza‐Diels–Alder Reaction
Rehan et al. Transition‐Metal‐Free Synthesis of Homo‐and Hetero‐1, 2, 4‐Triaryl Benzenes by an Unexpected Base‐Promoted Dearylative Pathway
Yao et al. Asymmetric N‐Allylic Alkylation of Hydrazones with Morita–Baylis–Hillman Carbonates
Zhang et al. Organocatalyzed Asymmetric Vinylogous Michael Reactions of 3, 5‐Dialkyl‐Substituted 4‐Nitroisoxazoles: A Direct Method for the Synthesis of Chiral Isoxazole Derivatives
Li et al. Organocatalyzed Formal [4+ 2] Cycloaddition of in situ Generated Azoalkenes with Arylacetic Acids: An Efficient Approach to the Synthesis of 4, 5‐Dihydropyridazin‐3 (2H)‐ones
Wu et al. Transition Metal‐Free Carbazole Synthesis from Arylureas and Cyclohexanones