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Hu et al., 2022 - Google Patents

Dual target inhibitors based on EGFR: Promising anticancer agents for the treatment of cancers (2017-)

Hu et al., 2022

Document ID
8137426082733276921
Author
Hu L
Fan M
Shi S
Song X
Wang F
He H
Qi B
Publication year
Publication venue
European Journal of Medicinal Chemistry

External Links

Snippet

The EGFR family play a significant role in cell signal transduction and their overexpression is implicated in the pathogenesis of numerous human solid cancers. Inhibition of the EGFR- mediated signaling pathways by EGFR inhibitors is a widely used strategy for the treatment …
Continue reading at www.sciencedirect.com (other versions)

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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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