Sankaran et al., 1979 - Google Patents
Preparation of biologically active radioiodinated cholecystokinin for radioreceptor assay and radioimmunoassay.Sankaran et al., 1979
View HTML- Document ID
- 8042322263178537565
- Author
- Sankaran H
- Deveney C
- Goldfine I
- Williams J
- Publication year
- Publication venue
- Journal of Biological Chemistry
External Links
Snippet
A modified method is described for the preparation of stable, high specific activity radioiodinated cholecystokinin (CCK) by its conjugation to 125I-Bolton Hunter reagent (125I- BH). Purified radioiodinated CCK (125I-BH-CCK) stimulated amylase release from isolate …
- 102100013472 CCK 0 title abstract description 106
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives
- A61K47/48—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
- A61K47/48369—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the modifying part being an antibody, an immunoglobulin, or a fragment thereof, e.g. a Fc-fragment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Sankaran et al. | Preparation of biologically active radioiodinated cholecystokinin for radioreceptor assay and radioimmunoassay. | |
ROBBINS et al. | Thyroxine transport proteins of plasma. Molecular properties and biosynthesis | |
Megyesi et al. | Insulin and non-suppressible insulin-like activity (NSILA-s): evidence for separate plasma membrane receptor sites | |
Robinson | The development and evaluation of a sensitive and specific radioimmunoassay for oxytocin in unextracted plasma | |
Lefkowitz et al. | ACTH receptors in the adrenal: specific binding of ACTH-125I and its relation to adenyl cyclase | |
Robbins et al. | Antibodies to covalent aggregates of insulin in blood of insulin-using diabetic patients | |
Filipsson et al. | Pituitary adenylate cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans | |
CASCIERI et al. | Serum half-life and biological activity of mutants of human insulin-like growth factor I which do not bind to serum binding proteins | |
AU3532889A (en) | Chimeric peptides for neuropeptide delivery through the blood-brain barrier | |
EP0015059A2 (en) | Immunochemical conjugates: method and composition | |
Segre et al. | [3] Development and application of sequence-specific radioimmunoassays for analysis of the metabolism of parathyroid hormone | |
Halme et al. | Gonadotropin receptors of human corpus luteum during menstrual cycle and pregnancy | |
Dockray et al. | Biological activity of iodinated gastrins | |
US4276206A (en) | Immunochemical conjugates: method and composition | |
Praissman et al. | Modification of the C-terminal octapeptide of cholecystokinin with a high-specific-activity lodinated imidoester: Preparation, characterization, and binding to isolated pancreatic acinar cells | |
Murray et al. | The immunochemical specificity of antisera to bovine parathyroid hormone: an approach to region-specific radioimmunoassay | |
Shoelson et al. | Circulating forms of somatostatinlike immunoreactivity in human plasma | |
Ohashi et al. | Pharmacokinetics of synthetic α-human atrial natriuretic polypeptide in normal men; effect of aging | |
Norman et al. | Radioimmunoassay studies with human growth hormone and a pituitary lipid mobilizing factor | |
North et al. | Radioimmunoassays for individual rat neurophysins | |
Rogozinski et al. | The nonenzymatic glycosylation of collagen | |
Maceda et al. | [125I] Diiodoinsulins: Binding Affinities, Biologic Potencies, and Properties of their Decay Products | |
Chang et al. | Radioimmunoassay of vasoactive intestinal polypeptide | |
Woltanski et al. | Radioiodination of Peptide Hormones and Immunoglobuline Preparations: Comparison of the Chloramine T and lodogen Method* | |
Ratanabanangkoon et al. | Properties of the phosphorylated beta subunit of human choriogonadotropin. |