[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Nueda et al., 2007 - Google Patents

The novel gene EGFL9/Dlk2, highly homologous to Dlk1, functions as a modulator of adipogenesis

Nueda et al., 2007

View PDF
Document ID
7786170518655840449
Author
Nueda M
Baladrón V
García-Ramírez J
Sánchez-Solana B
Ruvira M
Rivero S
Ballesteros M
Monsalve E
Díaz-Guerra M
Ruiz-Hidalgo M
Laborda J
Publication year
Publication venue
Journal of molecular biology

External Links

Snippet

The Dlk1 gene appears to function as a regulator of adipogenesis. Adult Dlk1-deficient mice are obese, but adipose tissue still develops in transgenic mice overexpressing an Fc-dlk1 fusion protein, and neither type of genetically modified mice displays serious abnormalities …
Continue reading at www.academia.edu (PDF) (other versions)

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602Vertebrate cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Hybridisation probes
    • C12Q1/6883Hybridisation probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40Regulators of development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants

Similar Documents

Publication Publication Date Title
Nueda et al. The EGF-like protein dlk1 inhibits notch signaling and potentiates adipogenesis of mesenchymal cells
Nueda et al. The novel gene EGFL9/Dlk2, highly homologous to Dlk1, functions as a modulator of adipogenesis
Yang et al. Lin28 promotes the proliferative capacity of neural progenitor cells in brain development
Clyne et al. Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes
Kamiya et al. Role of the hepatocyte nuclear factor 4α in control of the pregnane X receptor during fetal liver development
Garcés et al. Notch-1 controls the expression of fatty acid-activated transcription factors and is required for adipogenesis
Artner et al. MafB: an activator of the glucagon gene expressed in developing islet α-and β-cells
Birsoy et al. Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis
Mardaryev et al. Micro-RNA-31 controls hair cycle-associated changes in gene expression programs of the skin and hair follicle
Niakan et al. Novel role for the orphan nuclear receptor Dax1 in embryogenesis, different from steroidogenesis
Mi et al. MicroRNA‐139‐5p suppresses 3T3‐L1 preadipocyte differentiation through notch and IRS1/PI3K/Akt insulin signaling pathways
Barca-Mayo et al. Thyroid hormone receptor α and regulation of type 3 deiodinase
Marchildon et al. CCAAT/enhancer binding protein beta is expressed in satellite cells and controls myogenesis
Jakkaraju et al. TIPs are tension-responsive proteins involved in myogenic versus adipogenic differentiation
Denson et al. HNF3β and GATA-4 transactivate the liver-enriched homeobox gene, Hex
Shang et al. Constitutively active signal transducer and activator of transcription 5 can replace the requirement for growth hormone in adipogenesis of 3T3-F442A preadipocytes
Stålberg et al. Transfection of the multiple endocrine neoplasia type 1 gene to a human endocrine pancreatic tumor cell line inhibits cell growth and affects expression of JunD, δ-like protein 1/preadipocyte factor-1, proliferating cell nuclear antigen, and QM/Jif-1
Vonesch et al. Stage and tissue‐specific expression of the alcohol dehydrogenase 1 (Adh‐1) gene during mouse development
Fujimoto et al. GJB6, of which mutations underlie Clouston syndrome, is a potential direct target gene of p63
Krawetz et al. Wnt6 induces the specification and epithelialization of F9 embryonal carcinoma cells to primitive endoderm
Rivero et al. DLK2 is a transcriptional target of KLF4 in the early stages of adipogenesis
Hernández et al. Isolation and characterization of the mouse gene for the type 3 iodothyronine deiodinase
Lee et al. MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBP β and C/EBP δ
Wang et al. Identification and distribution of a novel platelet-derived growth factor receptor β variant: effect of retinoic acid and involvement in cell differentiation
Wei et al. MicroRNA-2400 promotes bovine preadipocyte proliferation