Beismann‐Driemeyer et al., 2004 - Google Patents
Function of the antigen transport complex TAP in cellular immunityBeismann‐Driemeyer et al., 2004
- Document ID
- 7698076968512268643
- Author
- Beismann‐Driemeyer S
- Tampé R
- Publication year
- Publication venue
- Angewandte Chemie International Edition
External Links
Snippet
The immune system consists of several kinds of cells and molecules whose complex interactions form an efficient system for the protection of an individual from outside invaders and its own transformed cells. Innate immunity refers to the immediate antimicrobial …
- 239000000427 antigen 0 title description 13
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Gewurz et al. | Human cytomegalovirus US2 endoplasmic reticulum-lumenal domain dictates association with major histocompatibility complex class I in a locus-specific manner | |
US20200407424A1 (en) | Novel complexes of types of mhc class ii that bind to collagen type ii peptides and their use on diagnosis and treatment | |
Busch et al. | Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression | |
Young | Killing of target cells by lymphocytes: a mechanistic view. | |
Hosken et al. | Defective presentation of endogenous antigen by a cell line expressing class I molecules | |
Mukherjee et al. | Efficient presentation of both cytosolic and endogenous transmembrane protein antigens on MHC class II is dependent on cytoplasmic proteolysis | |
Procko et al. | Identification of domain boundaries within the N‐termini of TAP1 and TAP2 and their importance in tapasin binding and tapasin‐mediated increase in peptide loading of MHC class I | |
Tobian et al. | Mycobacterium tuberculosis heat shock fusion protein enhances class I MHC cross-processing and-presentation by B lymphocytes | |
Purcell et al. | Association of stress proteins with autoantigens: a possible mechanism for triggering autoimmunity? | |
Oftung et al. | Mapping of multiple HLA class II-restricted T-cell epitopes of the mycobacterial 70-kilodalton heat shock protein | |
WO2019018796A1 (en) | Herpes simplex virus vaccine epitopes specifically recognized by tissue resident memory t cells | |
Lane-Serff et al. | Evolutionary diversification of the trypanosome haptoglobin-haemoglobin receptor from an ancestral haemoglobin receptor | |
Beismann‐Driemeyer et al. | Function of the antigen transport complex TAP in cellular immunity | |
CHUN et al. | Constitutive and regulated expression of the class Ib molecule Qa‐1 in pancreatic β cells | |
Sievers et al. | Glycoprotein B from strain 17 of herpes simplex virus type I contains an invariant chain homologous sequence that binds to MHC class II molecules | |
Schamel et al. | Identification of the immunodominant H-2Kk-restricted cytotoxic T-cell epitope in the Borna disease virus nucleoprotein | |
CA2418445A1 (en) | Stress proteins and peptides and methods of use thereof | |
Kim et al. | MR1-and HLA-E-dependent antigen presentation of mycobacterium tuberculosis | |
Parham | Molecular definition of the transplantation antigens | |
Harris et al. | Permissive recognition of a mycobacterial T-cell epitope: localization of overlapping epitope core sequences recognized in association with multiple major histocompatibility complex class II IA molecules | |
Sheil et al. | Identification of an autologous insulin B chain peptide as a target antigen for H-2Kb-restricted cytotoxic T lymphocytes. | |
Kim et al. | Molecular mechanisms of MHC class I-antigen processing: redox considerations | |
Bennink et al. | Antigen processing: where tumor-specific T-cell responses begin | |
Vitalis et al. | Using the TAP component of the antigen-processing machinery as a molecular adjuvant | |
Faiola et al. | Influence of CD4 T cells and the source of major histocompatibility complex class II‐restricted peptides on cytotoxic T‐cell priming by dendritic cells |