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Salazar‐Roa et al., 2020 - Google Patents

Transient exposure to miR‐203 enhances the differentiation capacity of established pluripotent stem cells

Salazar‐Roa et al., 2020

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Document ID
7638869070630813551
Author
Salazar‐Roa M
Trakala M
Álvarez‐Fernández M
Valdés‐Mora F
Zhong C
Muñoz J
Yu Y
Peters T
Graña‐Castro O
Serrano R
Zapatero‐Solana E
Abad M
Bueno M
de Cedrón M
Fernández‐Piqueras J
Serrano M
Blasco M
Wang D
Clark S
Izpisua‐Belmonte J
Ortega S
Malumbres M
Publication year
Publication venue
The EMBO Journal

External Links

Snippet

Full differentiation potential along with self‐renewal capacity is a major property of pluripotent stem cells (PSCs). However, the differentiation capacity frequently decreases during expansion of PSCs in vitro. We show here that transient exposure to a single …
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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    • C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
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