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Ren et al., 2019 - Google Patents

Role of liposome size, surface charge, and PEGylation on rheumatoid arthritis targeting therapy

Ren et al., 2019

Document ID
7621778687399566583
Author
Ren H
He Y
Liang J
Cheng Z
Zhang M
Zhu Y
Hong C
Qin J
Xu X
Wang J
Publication year
Publication venue
ACS applied materials & interfaces

External Links

Snippet

Rheumatoid arthritis (RA) is a chronic, systemic, progressive autoimmune disease. The vascular permeability of inflamed joints in RA makes it a natural candidate for passive targeting, similar to the enhanced permeability and retention (EPR) effect in solid tumors …
Continue reading at pubs.acs.org (other versions)

Classifications

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    • A61K47/48815Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the conjugate being characterized by a special physical or galenical form the form being a colloid, emulsion, i.e. having at least a dispersed/continuous oil phase and a dispersed/continuous aqueous phase, dispersion or suspension the form being a liposome, i.e. a bilayered vesicle, having its surface modified by covalent attachment or complexation of the pharmacologically or therapeutically active agent and/or modifying agent.
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