[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Shi et al., 2023 - Google Patents

Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane

Shi et al., 2023

View HTML
Document ID
7617494236896542041
Author
Shi W
Cai Y
Zhu H
Peng H
Voyer J
Rits-Volloch S
Cao H
Mayer M
Song K
Xu C
Lu J
Zhang J
Chen B
Publication year
Publication venue
Nature

External Links

Snippet

The entry of SARS-CoV-2 into host cells depends on the refolding of the virus-encoded spike protein from a prefusion conformation, which is metastable after cleavage, to a lower- energy stable postfusion conformation,. This transition overcomes kinetic barriers for fusion …
Continue reading at www.nature.com (HTML) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids

Similar Documents

Publication Publication Date Title
Shi et al. Cryo-EM structure of SARS-CoV-2 postfusion spike in membrane
Kirchdoerfer et al. Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis
Cai et al. Distinct conformational states of SARS-CoV-2 spike protein
Gobeil et al. D614G mutation alters SARS-CoV-2 spike conformation and enhances protease cleavage at the S1/S2 junction
Xu et al. Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM
Xiong et al. Close relatives of MERS-CoV in bats use ACE2 as their functional receptors
Zhang et al. Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution
Xiao et al. A trimeric human angiotensin-converting enzyme 2 as an anti-SARS-CoV-2 agent
Zhang et al. Structure of SARS-CoV-2 membrane protein essential for virus assembly
Tortorici et al. Structural basis for human coronavirus attachment to sialic acid receptors
Das et al. Direct visualization of the conformational dynamics of single influenza hemagglutinin trimers
Li et al. A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection
Walls et al. Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer
Wang et al. Conformational dynamics of the Beta and Kappa SARS-CoV-2 spike proteins and their complexes with ACE2 receptor revealed by cryo-EM
Ou et al. Crystal structure of the receptor binding domain of the spike glycoprotein of human betacoronavirus HKU1
Li et al. Acidic pH-induced conformations and LAMP1 binding of the Lassa virus glycoprotein spike
Cong et al. Coronavirus nucleocapsid proteins assemble constitutively in high molecular oligomers
Meier et al. The crystal structure of ORF-9b, a lipid binding protein from the SARS coronavirus
Henderson et al. Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements
Chakraborti et al. The SARS coronavirus S glycoprotein receptor binding domain: fine mapping and functional characterization
Newton et al. The structure of an infectious immature flavivirus redefines viral architecture and maturation
Park et al. Interactions of SARS-CoV-2 envelope protein with amilorides correlate with antiviral activity
Calvaresi et al. Structural dynamics in the evolution of SARS-CoV-2 spike glycoprotein
Kumar et al. Structure of the human secretory immunoglobulin M core
Song et al. Cryo-EM analysis of the HCoV-229E spike glycoprotein reveals dynamic prefusion conformational changes