Ekroos, 2012 - Google Patents
Lipidomics: technologies and applicationsEkroos, 2012
- Document ID
- 7617470288068355102
- Author
- Ekroos K
- Publication year
External Links
Snippet
Focusing on the practical applications, this user-oriented guide presents current technologies and strategies for systems-level lipid analysis, going beyond basic research to concentrate on commercial uses of lipidomics in biomarker and diagnostic development, as …
- 150000002632 lipids 0 abstract description 454
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
- G01N2405/04—Phospholipids, i.e. phosphoglycerides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
- G01N2405/08—Sphingolipids
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Ekroos | Lipidomics: technologies and applications | |
Holčapek et al. | Lipidomic analysis | |
Bou Khalil et al. | Lipidomics era: accomplishments and challenges | |
Williams et al. | Pinpointing double bond and sn-positions in glycerophospholipids via hybrid 193 nm ultraviolet photodissociation (UVPD) mass spectrometry | |
Spickett et al. | Oxidative lipidomics coming of age: advances in analysis of oxidized phospholipids in physiology and pathology | |
Loizides‐Mangold | On the future of mass‐spectrometry‐based lipidomics | |
Han | Lipidomics: Comprehensive mass spectrometry of lipids | |
Ryan et al. | Chemical derivatization and ultrahigh resolution and accurate mass spectrometry strategies for “shotgun” lipidome analysis | |
Han et al. | Multi‐dimensional mass spectrometry‐based shotgun lipidomics and novel strategies for lipidomic analyses | |
Rampler et al. | A novel lipidomics workflow for improved human plasma identification and quantification using RPLC-MSn methods and isotope dilution strategies | |
Bonney et al. | Perspective on emerging mass spectrometry technologies for comprehensive lipid structural elucidation | |
Murphy et al. | Mass spectrometric analysis of long‐chain lipids | |
Vale et al. | Three-phase liquid extraction: a simple and fast method for lipidomic workflows [S] | |
Cífková et al. | Nontargeted quantitation of lipid classes using hydrophilic interaction liquid chromatography–electrospray ionization mass spectrometry with single internal standard and response factor approach | |
Castro-Perez et al. | Comprehensive LC− MSE lipidomic analysis using a shotgun approach and its application to biomarker detection and identification in osteoarthritis patients | |
Fhaner et al. | Comprehensive lipidome profiling of isogenic primary and metastatic colon adenocarcinoma cell lines | |
Li et al. | Analytical methods in lipidomics and their applications | |
Yang et al. | Automated lipid identification and quantification by multidimensional mass spectrometry-based shotgun lipidomics | |
Wang et al. | Applications of mass spectrometry for cellular lipid analysis | |
Han et al. | Characterization and direct quantitation of cerebroside molecular species from lipid extracts by shotgun lipidomics | |
Reis | Oxidative Phospholipidomics in health and disease: Achievements, challenges and hopes | |
Bird et al. | Qualitative characterization of the rat liver mitochondrial lipidome using LC–MS profiling and high energy collisional dissociation (HCD) all ion fragmentation | |
Nakanishi et al. | Separation and quantification of sn-1 and sn-2 fatty acid positional isomers in phosphatidylcholine by RPLC-ESIMS/MS | |
Postle et al. | Probing phospholipid dynamics by electrospray ionisation mass spectrometry | |
Scherer et al. | Simultaneous quantification of cardiolipin, bis (monoacylglycero) phosphate and their precursors by hydrophilic interaction LC− MS/MS including correction of isotopic overlap |