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Cerqueira et al., 2013 - Google Patents

Microglia response and in vivo therapeutic potential of methylprednisolone‐loaded dendrimer nanoparticles in spinal cord injury

Cerqueira et al., 2013

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Document ID
7609926169309598017
Author
Cerqueira S
Oliveira J
Silva N
Leite‐Almeida H
Ribeiro‐Samy S
Almeida A
Mano J
Sousa N
Salgado A
Reis R
Publication year
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The control and manipulation of cells that trigger secondary mechanisms following spinal cord injury (SCI) is one of the first opportunities to minimize its highly detrimental outcomes. Herein, the ability of surface‐engineered carboxymethylchitosan/polyamidoamine …
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    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5146Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153Polyesters, e.g. poly(lactide-co-glycolide)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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