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Muthu Raja et al., 2012 - Google Patents

Functionally suppressive CD8 T regulatory cells are increased in patients with multiple myeloma: a cause for immune impairment

Muthu Raja et al., 2012

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Document ID
7599731282057138855
Author
Muthu Raja K
Kubiczkova L
Rihova L
Piskacek M
Vsianska P
Hezova R
Pour L
Hajek R
Publication year
Publication venue
PloS one

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Snippet

Background Multiple myeloma (MM) is a plasma cell malignancy frequently associated with impaired immune cell numbers and functions. In MM, several studies have previously shown that CD4 regulatory T (Treg) cells hamper effector T cell functions and enhance immune …
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    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/53Immunoassay; Biospecific binding assay
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    • G01N33/574Immunoassay; Biospecific binding assay for cancer
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    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/53Immunoassay; Biospecific binding assay
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