[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Vanshylla et al., 2018 - Google Patents

Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells

Vanshylla et al., 2018

View HTML
Document ID
7404173728548046022
Author
Vanshylla K
Bartsch C
Hitzing C
Krümpelmann L
Wienands J
Engels N
Publication year
Publication venue
Scientific reports

External Links

Snippet

The B cell antigen receptor (BCR) employs enzymatically inactive adaptor proteins to facilitate activation of intracellular signaling pathways. In animal model systems, adaptor proteins of the growth factor receptor-bound 2 (Grb2) family have been shown to serve …
Continue reading at www.nature.com (HTML) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/564—Immunoassay; Biospecific binding assay for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/574—Immunoassay; Biospecific binding assay for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes

Similar Documents

Publication Publication Date Title
Vanshylla et al. Grb2 and GRAP connect the B cell antigen receptor to Erk MAP kinase activation in human B cells
Li et al. Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases
Lo et al. Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT
Wahl et al. Phosphorylation of two regulatory tyrosine residues in the activation of Bruton’s tyrosine kinase via alternative receptors
Tsang et al. Molecular mechanism of the Syk activation switch
D'Silva et al. Role of Pam16's degenerate J domain in protein import across the mitochondrial inner membrane
Wang et al. Identification of novel interaction sites that determine specificity between fibroblast growth factor homologous factors and voltage-gated sodium channels
Bultynck et al. Thimerosal stimulates Ca2+ flux through inositol 1, 4, 5-trisphosphate receptor type 1, but not type 3, via modulation of an isoform-specific Ca2+-dependent intramolecular interaction
Chiu et al. BLNK: molecular scaffolding through ‘cis’‐mediated organization of signaling proteins
Taguchi et al. Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission
Kimura et al. Expression of SLC2A9 isoforms in the kidney and their localization in polarized epithelial cells
Yarden et al. BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage
Chatellard-Causse et al. Alix (ALG-2-interacting protein X), a protein involved in apoptosis, binds to endophilins and induces cytoplasmic vacuolization
Xia et al. Dominant role of CDKN2B/p15INK4B of 9p21. 3 tumor suppressor hub in inhibition of cell-cycle and glycolysis
Sturany et al. Mechanism of activation of protein kinase D2 (PKD2) by the CCKB/gastrin receptor
Talcott et al. The nuclear import of RCC1 requires a specific nuclear localization sequence receptor, karyopherin α3/Qip
Biterge et al. Methylation of histone H4 at aspartate 24 by protein L-isoaspartate O-methyltransferase (PCMT1) links histone modifications with protein homeostasis
Von Nicolai et al. A second DNA binding site in human BRCA2 promotes homologous recombination
Lubert et al. Interaction between protein phosphatase 5 and the A subunit of protein phosphatase 2A: evidence for a heterotrimeric form of protein phosphatase 5
Busman-Sahay et al. Cis and trans regulatory mechanisms control AP2-mediated B cell receptor endocytosis via select tyrosine-based motifs
Kruyt et al. Resistance to mitomycin C requires direct interaction between the Fanconi anemia proteins FANCA and FANCG in the nucleus through an arginine-rich domain
Teimer et al. A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex
Liang et al. Tespa1 regulates T cell receptor-induced calcium signals by recruiting inositol 1, 4, 5-trisphosphate receptors
Wolting et al. Biochemical and computational analysis of LNX1 interacting proteins
Wang et al. Testis-specific serine/threonine protein kinase 4 (Tssk4) phosphorylates Odf2 at Ser-76