Fang et al., 2014 - Google Patents
Enhanced bacterial tumor delivery by modulating the EPR effect and therapeutic potential of Lactobacillus caseiFang et al., 2014
View PDF- Document ID
- 7396014147289996195
- Author
- Fang J
- Liao L
- Yin H
- Nakamura H
- Shin T
- Maeda H
- Publication year
- Publication venue
- Journal of pharmaceutical sciences
External Links
Snippet
Bacteria of micrometer size could accumulate in tumor based on enhanced permeability and retention (EPR) effect. We report here Lactobacillus casei (L. casei), a nonpathogenic facultatively anaerobic bacterium, preferentially accumulated in tumor tissues after …
- 206010028980 Neoplasm 0 title abstract description 152
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Micro-organisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
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- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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