Fourrière et al., 2010 - Google Patents
Synthesis of difluorinated carbocyclic analogues of 5-deoxypentofuranoses and 1-amino-5-deoxypentofuranoses: en route to fluorinated carbanucleosidesFourrière et al., 2010
- Document ID
- 724207579289856992
- Author
- Fourrière G
- Van Hijfte N
- Lalot J
- Dutech G
- Fragnet B
- Coadou G
- Quirion J
- Leclerc E
- Publication year
- Publication venue
- Tetrahedron
External Links
Snippet
The synthesis of difluorinated carbocyclic analogues of 5-deoxypentofuranoses and 1- amino-5-deoxypentofuranoses is described. The sequence involves an addition of PhSeCF2TMS to carbohydrate-derived aldehydes or their corresponding tert …
- 238000003786 synthesis reaction 0 title abstract description 13
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2101/00—Systems containing only non-condensed rings
- C07C2101/12—Systems containing only non-condensed rings with a six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Renard et al. | Synthesis and properties of spiro nucleosides containing the barbituric acid moiety | |
Teng et al. | Synthesis and biological evaluation of novel sinomenine derivatives as anti-inflammatory agents | |
Dangroo et al. | An efficient synthesis of phosphoramidates from halides in aqueous ethanol | |
Chong et al. | A divergent synthesis of D-and L-carbocyclic 4′-fluoro-2′, 3′-dideoxynucleosides as potential antiviral agents | |
Fei et al. | Synthesis of [18F] Xeloda as a novel potential PET radiotracer for imaging enzymes in cancers | |
Pham et al. | Methyl (S)-lactate as a chiral auxiliary in the asymmetric synthesis of Bao Gong Teng A | |
Zheng et al. | Comparative studies of potential cancer biomarkers carbon-11 labeled MMP inhibitors (S)-2-(4′-[11C] methoxybiphenyl-4-sulfonylamino)-3-methylbutyric acid and N-hydroxy-(R)-2-[[(4′-[11C] methoxyphenyl) sulfonyl] benzylamino]-3-methylbutanamide | |
Tanaka et al. | Efficient synthesis of 2, 6, 9-triazabicyclo [3.3. 1] nonanes through amine-mediated formal [4+ 4] reaction of unsaturated imines | |
Wang et al. | Syntheses and evaluation of fluorinated conformationally restricted analogues of GABA as potential inhibitors of GABA aminotransferase | |
Fourrière et al. | Synthesis of difluorinated carbocyclic analogues of 5-deoxypentofuranoses and 1-amino-5-deoxypentofuranoses: en route to fluorinated carbanucleosides | |
Gauvry et al. | A short stereoselective preparation of dienamides from cyclobutene compounds. Application in the synthesis of a new cyclohexene nucleoside | |
Heard et al. | Synthesis of a Novel N-Hydroxypyrrole via Lithium Perchlorate Accelerated Diels-Alder Methodology | |
Janecki et al. | 4-Methylideneisoxazolidin-5-ones—A new class of α-methylidene-γ-lactones with high cytostatic activity | |
Richichi et al. | Stereoselective synthesis of new bicyclic N, O-iso-homonucleoside analogues | |
JP2023527213A (en) | triazolone compounds | |
Kumamoto et al. | Synthesis of (±)-4′-ethynyl-5′, 5′-difluoro-2′, 3′-dehydro-3′-deoxy-carbocyclic thymidine: a difluoromethylidene analogue of promising anti-HIV agent Ed4T | |
Kotha et al. | Synthesis of benzocycloheptene-based amino acid derivatives via a [4+ 2] cycloaddition reaction as a key step | |
Fourrière et al. | Synthesis of exo-methylenedifluorocyclopentanes as precursors of fluorinated carbasugars by 5-exo-dig radical cyclization | |
Das et al. | Racemic 2, 4-di-O-benzoyl-myo-inositol 1, 3, 5-orthoformate: a versatile intermediate for the preparation of myo-inositol phosphates | |
Viña et al. | 1, 2-Disubstituted cyclohexane nucleosides: comparative study for the synthesis of cis and trans adenosine analogues | |
Blanco et al. | Divergent synthesis of two precursors of 3′-homo-2′-deoxy-and 2′-homo-3′-deoxy-carbocyclic nucleosides | |
Duke et al. | Synthesis and resolution of 2-methyl analogues of GABA | |
Barotcu et al. | Stereoselective synthesis of novel bis-homoinositols with bicyclo [4.2. 0] octane motifs | |
Chen et al. | Vicarious nucleophilic substitution of 1-benzyl-5-nitroimidazole, application to the synthesis of 6, 7-dihydroimidazo [4, 5-d][1, 3] diazepin-8 (3H)-one | |
Tănase et al. | New carbocyclic nucleoside analogues with a bicyclo [2.2. 1] heptane fragment as sugar moiety; synthesis, X-ray crystallography and anticancer activity |