Weber et al., 1995 - Google Patents
Requirement for peptide in alloreactive CD4+ T cell recognition of class II MHC molecules.Weber et al., 1995
View PDF- Document ID
- 7238020660795397725
- Author
- Weber D
- Terrell N
- Zhang Y
- Strindberg G
- Martin J
- Rudensky A
- Braunstein N
- Publication year
- Publication venue
- Journal of immunology (Baltimore, Md.: 1950)
External Links
Snippet
To examine the role of peptide in alloreactive class II MHC-restricted responses, we transfected IA molecules into the Ag-processing defective mutant cell line, T2. Consistent with their defective Ag-processing phenotype, the T2 transfectants predominantly express …
- 230000005859 cell recognition 0 title description 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70539—MHC-molecules, e.g. HLA-molecules
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Connolly et al. | The Lyt-2 molecule recognizes residues in the class I alpha 3 domain in allogeneic cytotoxic T cell responses. | |
| Ellis et al. | T cell mimicry and epitope specificity of cross-reactive T cell clones from rheumatic heart disease | |
| Weber et al. | Requirement for peptide in alloreactive CD4+ T cell recognition of class II MHC molecules. | |
| Felix et al. | Specificity of T-cell alloreactivity | |
| Joosten et al. | Mycobacterium tuberculosis peptides presented by HLA-E molecules are targets for human CD8+ T-cells with cytotoxic as well as regulatory activity | |
| Choi et al. | Quantitative analysis of the immune response to mouse non-MHC transplantation antigens in vivo: the H60 histocompatibility antigen dominates over all others | |
| McCaughan et al. | Detecting donor-specific antibodies: the importance of sorting the wheat from the chaff | |
| Zhou et al. | Presentation of acquired peptide-MHC class II ligands by CD4+ regulatory T cells or helper cells differentially regulates antigen-specific CD4+ T cell response | |
| Tynan et al. | The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation | |
| Millrain et al. | Examination of HY response: T cell expansion, immunodominance, and cross-priming revealed by HY tetramer analysis | |
| CN109485721A (en) | A method of obtaining tumor specific T cells receptor | |
| Schuster et al. | Allorestricted T cells with specificity for the FMNL1-derived peptide PP2 have potent antitumor activity against hematologic and other malignancies | |
| Norimine et al. | Intrahaplotype and interhaplotype pairing of bovine leukocyte antigen DQA and DQB molecules generate functional DQ molecules important for priming CD4+ T-lymphocyte responses | |
| Gaston et al. | Cross-reactivity of self-HLA-restricted Epstein-Barr virus-specific cytotoxic T lymphocytes for allo-HLA determinants. | |
| Liu et al. | Indirect recognition of donor MHC class II antigens in human transplantation | |
| Zhang et al. | A polyclonal anti‐vaccine CD4 T cell response detected with HLA‐DP4 multimers in a melanoma patient vaccinated with MAGE‐3. DP4‐peptide‐pulsed dendritic cells | |
| Joshi et al. | Flexibility in MHC and TCR recognition: degenerate specificity at the T cell level in the recognition of promiscuous Th epitopes exhibiting no primary sequence homology | |
| Colovai et al. | New approaches to specific immunomodulation in transplantation | |
| Ciccone et al. | General role of HLA class I molecules in the protection of target cells from lysis by natural killer cells: evidence that the free heavy chains of class I molecules are not sufficient to mediate the protective effect | |
| Provenzano et al. | Identification of immune dominant cytomegalovirus epitopes using quantitative real-time polymerase chain reactions to measure interferon-γ production by peptide-stimulated peripheral blood mononuclear cells | |
| Lam et al. | Human T cell receptor-gamma delta-expressing T-cell lines recognize MHC-controlled elements on autologous EBV-LCL that are not HLA-A,-B,-C,-DR,-DQ, or-DP. | |
| Stastny et al. | Evaluation of the highly sensitized transplant recipient | |
| Khan | Ankylosing spondylitis and heterogeneity of HLA-B27 | |
| Rockinger et al. | Optimized combinatorial pMHC class II multimer labeling for precision immune monitoring of tumor-specific CD4 T cells in patients | |
| Huang et al. | A patient-derived cytotoxic T-lymphocyte clone and two peptide-dependent monoclonal antibodies recognize HLA-B27-peptide complexes with low stringency for peptide sequences |