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Bogolubsky et al., 2015 - Google Patents

Facile one-pot synthesis of 4-substituted semicarbazides

Bogolubsky et al., 2015

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Document ID
7167048839224091725
Author
Bogolubsky A
Moroz Y
Mykhailiuk P
Dmytriv Y
Pipko S
Babichenko L
Konovets A
Tolmachev A
Publication year
Publication venue
RSC Advances

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Snippet

A diverse library of twenty-five 4-mono-and disubstituted semicarbazides was prepared in a one-pot two-step approach. The method includes formation of a carbamate from bis (2, 2, 2- trifluoroethyl) carbonate or 2, 2, 2-trifluoroethylchloroformate and a primary or secondary …
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
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