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Hubert Jr et al., 2011 - Google Patents

Xpa deficiency reduces CAG trinucleotide repeat instability in neuronal tissues in a mouse model of SCA1

Hubert Jr et al., 2011

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Document ID
7159314458536140264
Author
Hubert Jr L
Lin Y
Dion V
Wilson J
Publication year
Publication venue
Human molecular genetics

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Expansion of trinucleotide repeats (TNRs) is responsible for a number of human neurodegenerative disorders. The molecular mechanisms that underlie TNR instability in humans are not clear. Based on results from model systems, several mechanisms for …
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