Ferguson et al., 2022 - Google Patents
Application of SFC for the characterization of formulated drug productsFerguson et al., 2022
- Document ID
- 7097206785109907391
- Author
- Ferguson P
- Cross R
- Schad G
- Publication year
- Publication venue
- Separation Science and Technology
External Links
Snippet
The peer-reviewed literature reporting characterization of pharmaceutical compounds by SFC principally focuses on drug substances or active pharmaceutical ingredients. For the technique to become more broadly adopted in the industry, demonstration of alternative …
- 239000000825 pharmaceutical preparation 0 title abstract description 32
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8665—Signal analysis for calibrating the measuring apparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/90—Plate chromatography, e.g. thin layer or paper chromatography
- G01N30/94—Development
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/60—Construction of the column
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/28—Control of physical parameters of the fluid carrier
- G01N30/30—Control of physical parameters of the fluid carrier of temperature
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Holm et al. | Analytical advances in pharmaceutical impurity profiling | |
| Görög | Critical review of reports on impurity and degradation product profiling in the last decade | |
| Desfontaine et al. | Supercritical fluid chromatography in pharmaceutical analysis | |
| Xue et al. | Quantitative determination of pioglitazone in human serum by direct-injection high-performance liquid chromatography mass spectrometry and its application to a bioequivalence study | |
| Schilling et al. | Recent applications of the Charged Aerosol Detector for liquid chromatography in drug quality control | |
| Iguiniz et al. | On-line coupling of achiral reversed phase liquid chromatography and chiral supercritical fluid chromatography for the analysis of pharmaceutical compounds | |
| Bian et al. | Fast and versatile analysis of liposome encapsulation efficiency by nanoParticle exclusion chromatography | |
| Malavasi et al. | Determination of amisulpride, a new benzamide derivative, in human plasma and urine by liquid-liquid extraction or solid-phase extraction in combination with high-performance liquid chromatography and fluorescence detection application to pharmacokinetics | |
| Rosetti et al. | Single-run reversed-phase HPLC method for determining sertraline content, enantiomeric purity, and related substances in drug substance and finished product | |
| Eom et al. | Rapid chiral separation of racemic cetirizine in human plasma using subcritical fluid chromatography-tandem mass spectrometry | |
| Al-Shehri et al. | Development and validation of an UHPLC-MS/MS method for simultaneous determination of palbociclib, letrozole and its metabolite carbinol in rat plasma and pharmacokinetic study application | |
| Hegade et al. | Development of an achiral-chiral 2-dimensional heart-cutting platform for enhanced pharmaceutical impurity analysis | |
| Amin et al. | Ion-pairing and reversed phase liquid chromatography for the determination of three different quinolones: enrofloxacin, lomefloxacin and ofloxacin | |
| ZARGHI et al. | Rapid quantification of valsartan in human plasma by liquid chromatography using a monolithic column and a fluorescence detection: application for pharmacokinetic studies | |
| Ferrone et al. | Development and validation of a MEPS-UHPLC-PDA method for determination of ulifloxacin in human plasma and urine of patients with peripheral arterial disease | |
| Xin et al. | Turbulent-flow chromatography coupled on-line to fast high-performance liquid chromatography and mass spectrometry for simultaneous determination of verticine, verticinone and isoverticine in rat plasma | |
| Orlando et al. | Simple and efficient method for enantioselective determination of omeprazole in human plasma | |
| Ferguson et al. | Application of SFC for the characterization of formulated drug products | |
| Yang et al. | Simultaneous quantitation of the diastereoisomers of scholarisine and 19‐epischolarisine, vallesamine, and picrinine in rat plasma by supercritical fluid chromatography with tandem mass spectrometry and its application to a pharmacokinetic study | |
| Li et al. | Ultra-performance liquid chromatography–tandem mass spectrometric method for the determination of Artemisinin in rat serum and its application in pharmacokinetics | |
| He et al. | Advancing stereoisomeric separation of an atropisomeric Bruton's tyrosine kinase inhibitor by using sub-2 µm immobilized polysaccharide-based chiral columns in supercritical fluid chromatography | |
| JP2018146313A (en) | Dissolution test method for soft capsules containing nalfurafine hydrochloride | |
| Arghavani-Beydokhti et al. | Application of a tandem air-agitated liquid–liquid microextraction technique based on solidification of floating organic droplets as an efficient extraction method for determination of cholesterol-lowering drugs in complicated matrices | |
| Medvedovici et al. | A non-extracting procedure for the determination of meloxicam in plasma samples by HPLC-diode array detection | |
| Zhang et al. | The validation of an LC-MS method for the determination of risperidone and its active metabolite 9-hydroxyrisperidone in human plasma |