How, 2015 - Google Patents
Body feed filtration provides enhanced bioprocessingHow, 2015
- Document ID
- 6990952287422273901
- Author
- How B
- Publication year
- Publication venue
- Biotechnology
External Links
Snippet
Continuous improvements in growth media and cell lines have elevated biomass concentrations in bioprocesses, subsequently challenging the downstream purification process. Sartorius Stedim Biotech's body feed filtration-based solution is designed to …
- 238000001914 filtration 0 title abstract description 16
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
- C12M47/04—Cell isolation or sorting
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Micro-organisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving micro-organisms or compositions thereof; Processes of preparing or isolating a composition containing a micro-organism; Culture media therefor
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Zydney | New developments in membranes for bioprocessing–A review | |
| Zydney | Continuous downstream processing for high value biological products: a review | |
| KR101680181B1 (en) | Methods and systems for manipulating particles using a fluidized bed | |
| EP2732021B1 (en) | Improved depth filters for disposable biotechnological processes | |
| KR102427715B1 (en) | Rapid harvesting of alternating tangential flow | |
| JP6676073B2 (en) | Continuous elution of products from chromatography columns | |
| US10494421B2 (en) | System, apparatus and method for biomolecules production | |
| JP2018504931A (en) | Cell and / or cell product manufacturing system, manufacturing apparatus, and manufacturing method | |
| US20130115588A1 (en) | Integrated bioreactor and separation system and methods of use therof | |
| TWI767930B (en) | Methods of processing a fluid including a recombinant therapeutic protein and use thereof | |
| JP7568638B2 (en) | Continuous production of recombinant proteins | |
| US20160200761A1 (en) | Buoyant protein harvesting device | |
| JP2022058979A (en) | Virus filtration | |
| KR102655056B1 (en) | Process technologies for manufacturing and downstream purification of biological products | |
| WO2021150996A1 (en) | Methods for harvesting biomolecules | |
| Berthold et al. | Interaction of cell culture with downstream purification: a case study | |
| How | Body feed filtration provides enhanced bioprocessing | |
| JP6758194B2 (en) | High cell density fill and draw fermentation process | |
| JP2023145471A (en) | In-line product concentration to reduce volumetric load flow rate and increase productivity of bind and elute chromatography purification | |
| US20210107938A1 (en) | Polypeptide separation method, polypeptide production method, and polypeptide purification device | |
| JP2023501693A (en) | Viral vector preparation method | |
| US20220169991A1 (en) | Viral vector purification apparatus and method | |
| CN103525866A (en) | Method for preparing plasmids | |
| EP4400583A1 (en) | Method for generating and purifying viral vectors | |
| van der Meer et al. | Single-Use Clarification System for High-Density Cell Cultures |