Xu et al., 2012 - Google Patents
Ab initio protein structure assembly using continuous structure fragments and optimized knowledge‐based force fieldXu et al., 2012
View PDF- Document ID
- 6947915822064512728
- Author
- Xu D
- Zhang Y
- Publication year
- Publication venue
- Proteins: Structure, Function, and Bioinformatics
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Ab initio protein folding is one of the major unsolved problems in computational biology owing to the difficulties in force field design and conformational search. We developed a novel program, QUARK, for template‐free protein structure prediction. Query sequences are …
- 102000004169 proteins and genes 0 title abstract description 107
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- G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
- G06F19/10—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology
- G06F19/16—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for molecular structure, e.g. structure alignment, structural or functional relations, protein folding, domain topologies, drug targeting using structure data, involving two-dimensional or three-dimensional structures
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- G06F19/22—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for sequence comparison involving nucleotides or amino acids, e.g. homology search, motif or SNP [Single-Nucleotide Polymorphism] discovery or sequence alignment
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