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Lesch et al., 1990 - Google Patents

Subsensitivity of the 5-hydroxytryptamine1A (5-HT1A) receptor-mediated hypothermic response to ipsapirone in unipolar depression

Lesch et al., 1990

Document ID
6600830600381837413
Author
Lesch K
Mayer S
Disselkamp-Tietze J
Hoh A
Schoellnhammer G
Schulte H
Publication year
Publication venue
Life sciences

External Links

Snippet

The selective 5-HT 1A receptor ligand ipsapirone (IPS) induces hypothermia in humans. To explore 5-HT 1A receptor-mediated thermoregulation in depression, 24 subjects (12 patients with unipolar depression and 12 individually matched controls) received 0.3 mg/kg IPS or …
Continue reading at www.sciencedirect.com (other versions)

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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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