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Bartuzi et al., 2023 - Google Patents

Illuminating the “twilight zone”: advances in difficult protein modeling

Bartuzi et al., 2023

Document ID
6485352215448515570
Author
Bartuzi D
Kaczor A
Matosiuk D
Publication year
Publication venue
Homology Modeling: Methods and Protocols

External Links

Snippet

Homology modeling was long considered a method of choice in tertiary protein structure prediction. However, it used to provide models of acceptable quality only when templates with appreciable sequence identity with a target could be found. The threshold value was …
Continue reading at link.springer.com (other versions)

Classifications

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    • G06F19/16—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for molecular structure, e.g. structure alignment, structural or functional relations, protein folding, domain topologies, drug targeting using structure data, involving two-dimensional or three-dimensional structures
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    • G06F19/22—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for sequence comparison involving nucleotides or amino acids, e.g. homology search, motif or SNP [Single-Nucleotide Polymorphism] discovery or sequence alignment
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