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Yang et al., 2023 - Google Patents

Neuroprotective effect of astragalin via activating PI3K/Akt-mTOR-mediated autophagy on APP/PS1 mice

Yang et al., 2023

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Document ID
6418950147779112023
Author
Yang C
Wang S
Zhang R
Lin J
Tian Y
Yang Y
Liu J
Ma Y
Publication year
Publication venue
Cell Death Discovery

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Snippet

As a small molecule flavonoid, astragalin (AST) has anti-inflammatory, anti-cancer, and anti- oxidation effects. However, the impact and molecular mechanism of AST in Alzheimer's disease (AD) are still not clear. This study aims to investigate the neuroprotective effect and …
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
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