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Matsumoto et al., 1999 - Google Patents

Blockade of the mitochondrial permeability transition pore diminishes infarct size in the rat after transient middle cerebral artery occlusion

Matsumoto et al., 1999

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Document ID
6073039448826910949
Author
Matsumoto S
Friberg H
Ferrand-Drake M
Wieloch T
Publication year
Publication venue
Journal of Cerebral Blood Flow & Metabolism

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Snippet

The mitochondrial permeability transition pore is an inducer of cell death. During the reperfusion phase after cerebral ischemia, calcium accumulates in mitochondria, and a burst of free radical formation occurs, conditions that favor the activation of the mitochondrial …
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