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Berent et al., 1981 - Google Patents

Mechanism of activation of glucocerebrosidase by co-β-glucosidase (glucosidase activator protein)

Berent et al., 1981

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Document ID
5882770222398297015
Author
Berent S
Radin N
Publication year
Publication venue
Biochimica et Biophysica Acta (BBA)-Lipids and Lipid Metabolism

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The nature of the stimulatory action of the protein 'coglucosidase'on gluco-cerebrosidase was investigated with the use of highly purified cofactor from bovine spleen, radioactive glucosyl ceramide and methylumbelliferyl-β-glucoside. A complex between coglucosidase …
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
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    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases Endopeptidases (3.4.21-3.4.25) derived from animal tissue
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