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Hammerer et al., 2019 - Google Patents

Controlling the regioselectivity of fatty acid hydroxylation (C10) at α‐and β‐Position by CYP152A1 (P450Bsβ) variants

Hammerer et al., 2019

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Document ID
5461572423787247985
Author
Hammerer L
Friess M
Cerne J
Fuchs M
Steinkellner G
Gruber K
Vanhessche K
Plocek T
Winkler C
Kroutil W
Publication year
Publication venue
ChemCatChem

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Regioselective hydroxylation on inactivated C− H bonds is among the dream reactions of organic chemists. Cytochrome P450 enzymes (CYPs) perform this reaction in general with high regio‐and stereoselectivity (eg for steroids as substrates). Furthermore, enzyme …
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