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Lu et al., 2014 - Google Patents

Development and evaluation of transferrin-stabilized paclitaxel nanocrystal formulation

Lu et al., 2014

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Document ID
5452858116183754016
Author
Lu Y
Wang Z
Li T
McNally H
Park K
Sturek M
Publication year
Publication venue
Journal of Controlled Release

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Snippet

The aim of the present study was to prepare and evaluate a paclitaxel nanocrystal-based formulation stabilized by serum protein transferrin in a non-covalent manner. The pure paclitaxel nanocrystals were first prepared using an antisolvent precipitation method …
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
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    • A61K9/513—Organic macromolecular compounds; Dendrimers
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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