[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

Rinehart et al., 1992 - Google Patents

Synthesis and properties of the eight isostatine stereoisomers

Rinehart et al., 1992

Document ID
5451732773991408017
Author
Rinehart K
Sakai R
Kishore V
Sullins D
Li K
Publication year
Publication venue
The Journal of Organic Chemistry

External Links

Snippet

The eight possible stereoisomers of isostatine,(3S, 4P, 5S)-4-amino-3-hydroxy-5- methylheptanoic acid, have been synthesizedfrom the four isomeric D-and L-isoleucinals and d-and L-olZo-isoleucinals and ethyl lithioacetate. The eight isomers have been …
Continue reading at pubs.acs.org (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof

Similar Documents

Publication Publication Date Title
Rinehart et al. Synthesis and properties of the eight isostatine stereoisomers
Namikoshi et al. Structures of three new cyclic heptapeptide hepatotoxins produced by the cyanobacterium (blue-green alga) Nostoc sp. strain 152
Sakai et al. Seven new didemnins from the marine tunicate Trididemnum solidum
Namikoshi et al. Seven more microcystins from homer lake cells: Application of the general method for structure assignment of peptides containing. Alpha.,. Beta.-dehydroamino acid unit (s)
Bray et al. Direct cleavage of peptides from a solid support into aqueous buffer. Application in simultaneous multiple peptide synthesis
Meyer et al. Use of proton nuclear magnetic resonance spectroscopy for sequence configuration analysis of cyclic tetrapeptides. Structure of tentoxin
AU731757B2 (en) Semi-synthetic studies toward didemnin analogues
US6034058A (en) Semi-synthetic alanyl dilemnin analogs
Baraguey et al. Isolation, structure and synthesis of chevalierins A, B and C, cyclic peptides from the latex of Jatropha chevalieri
DE69033257T2 (en) Cytotoxic cyclic depsipeptides of the tunicate Trididemnum Solidum
Nutt et al. Synthesis of dihydromauritine A, a reduced cyclopeptide alkaloid
KOBAYASHI et al. Studies on fungal products. XI. Isolation and structures of novel cyclic pentapeptides from Aspergillus sp. NE-45
DD200799A5 (en) PROCESS FOR THE PRODUCTION OF PEPTIDES
Pettit et al. Isolation and structure of the human cancer cell growth inhibitory cyclic decapeptides phakellistatins 7, 8 and 91, 2
NZ202784A (en) Enkephalin derivatives and pharmaceutical compositions
JP2004528268A (en) Derivatives of raspartmycin and their preparation and use
EP0589927A1 (en) Protected amino-acid unit, its preparation and its use
LU85710A1 (en) NOVEL GONADOLIBERIN DERIVATIVES AND PROCESS FOR THEIR PREPARATION
CALMES et al. Synthesis and biological activity of a destruxin analogue: d‐Lac‐6 destruxin E
AU666789B2 (en) 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, production and use thereof
US5478809A (en) TAN-1511, its derivatives, production and use thereof
Teshima et al. Chemical studies on tuberactinomycin. XII. Syntheses and antimicrobial activities of [Ala3, Ala4]-,[Ala3]-, and [Ala4]-tuberactinomycin O.
US3790555A (en) Octapeptide derivative of gonadotropinreleasing hormone
US4668397A (en) Novel cyclic octapeptide, method for production of said octapeptide, and ion extracting/separating agent using said octapeptide as principal component
Shin et al. Synthetic studies on quinoxaline antibiotics. Synthesis of quinoxaline-2-carbonyl tetradepsipeptide derivatives related to triostin A.